Prof. Dr. med. Roland Pfäffle
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Prof. Dr. med. Roland Pfäffle

Personal information

Pfäffle, Roland, Prof. Dr. med.
Department of Pediatrics, Medical Faculty
UL

Current position

Professor of Pediatric Endocrinology (since 2002)

Role within partner site

CrescNet registry and combination of etiology, epidemiological screening approaches of growth retardation

Relevant work experience

Pediatrician scientist in endocrinology

2010- Chief Scientific Officer of the CrescNet GmbH

1999-02 Lecturer for Pediatric Endocrinology & Diabetology, RWTH Aachen

1994-02 Senior Pediatrician, RWTH Aachen

1992- Molecular Biology & Endocrinology Lab (Children’s Hospital, RWTH Aachen, from 2002 at Department of Pediatrics, University Medical Center Leipzig, www.endogenet.org).

1987-94 Resident in Pediatrics, University Children’s Hospital, RWTH Aachen (paused for Fellowship from 1990-92)

Professional background

2006 Certification Child endocrinology and diabetology

1998 Habilitation in Pediatrics (RWTH Aachen, from 2002 in Leipzig)

1994 Board certification in Pediatrics

1990-92 Visiting Research Fellow, Emory University, Atlanta, Georgia, USA

1989 Foreign Medical Graduate Examination

1988 Research Doctorate (Dr. med., RWTH Aachen)

1980-86 Medical School, RWTH Aachen

Main research focus

Identification and characterization of transcription factors influencing the human embrionic development of the anterior pituitary; genetic causes of growth retardation with pituitary hormonal deficiency; GH and IGF-1 resistance; long-term effects and safety of treatment with recombinant human growth hormones (rhGH); automation and linkage of auxological screening methods for early detection of childhood disorders of growth and of weight development;

Publications

5 out of 131; WOS h-index 27

Felix JF, …, Pfäffle R et al. Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet 2016;25:389-403.

Blüher S, …, Pfäffle R et al. Age-specific stabilization in obesity prevalence in German children: A cross-sectional study from 1999 to 2008. Int J Pediatr Obes 2011;6:e199-e206.

Abuzzahab MJ, …, Pfäffle R et al. IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation. N Engl J Med 2003;349:2211-2222.

Wu W, … Pfäffle RW et al. Mutations in PROP1 cause familial combined pituitary hormone deficiency. Nat Genet 1998;18:147–149.

Pfäffle R et al. Mutation of the POU-specific domain of PIT-1 and hypopituarism without pituitary hypoplasia. Science 1992;257;1118-1121.

Additional information

Editorial Board: European Journal of Endocrinology, Journal Paediatric Endocrinology, Zeitschrift für Kinder- und Jugendmedizin; Awards: Friedrich-Wilhelm-Award for the Habilitation (RWTH Aachen, 1999), Friedrich-Linneweh-Award for Pediatric Research (1992); Stipends: International Scholarship of the German Research Foundation (1990-92)

SaxoChiLD

One Team – One Vision

Coordinator
Prof. Dr. med. Antje Körner
Leipzig University
Department of Pediatrics
Liebigstr. 20a
04103 Leipzig
Phone: +49 341 97 26500
E-Mail antje.koerner@medizin.uni-leipzig.de

Co-Coordinator
Prof. Dr. med. Reinhard Berner
University Hospital Carl Gustav Carus, TUD
Department of Pediatrics
Fetscherstr. 74
01307 Dresden
Phone: +49 351 458 2440
E-Mail: reinhard.berner@uniklinikum-dresden.de

 

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